Saturday, February 24, 2007

Obesity induced by Microwave Radiation, but helped by Acupuncture

Looks like the Japanese and the Chinese are ahead in this line of research! And the insurance companies are trying to claim that CFS is caused by obesity - good one! Blame the victim - of electromagnetic radiation exposure. That's the way to do it! Rather than looking at the real problem, create another one!


J Auton Nerv Syst. 1994 Aug;48(3):213-9. Links

Aspects of hypothalamic neuronal systems in VMH lesion-induced obese rats.

Takahashi A ,
Ishimaru H ,
Ikarashi Y ,
Maruyama Y .
Department of Neuropsychopharmacology (Tsumura), Gunma University School of Medicine, Japan.

To clarify neuronal disturbance in the hypothalamus reflecting the development of obesity in ventromedial hypothalamic nucleus (VMH)-lesioned rats, we investigated the contents of neurotransmitters in the hypothalamus after pretreatment by microwave irradiation, contents of neurotransmitter metabolites in third ventricle fluid and catecholamine contents in the adrenal gland. The hypothalamic contents of norepinephrine (NE) and dopamine (DA) were selectively decreased, but acetylcholine (ACh) and serotonin (5-HT) levels were not changed from those in controls. In the lateral part of the hypothalamus, also, a significant decrease of NE content was detected. On the other hand, NE and DA metabolites, MHPG, DOPAC and HVA were increased in the third ventricle fluid in VMH lesion-induced obese rats. Wet weight and content of epinephrine in the adrenal gland were decreased, though the content of NE was preserved. These results indicate that a disturbance of NE and DA neurons in the hypothalamus is involved in the development of VMH lesion-induced obesity. In addition, an increment of the activities of NE and DA systems in the central nervous system as a whole and some irregularity in the sympatho-adrenal system might contribute to VMH obesity.
PMID: 7963256 [PubMed - indexed for MEDLINE]

1: Brain Res Bull. 1995;36(1):97-9. Links

Decrease of norepinephrine and preservation of acetylcholine in the hypothalamus of VMH obese rats.

Takahashi A,
Ishimaru H,
Ikarashi Y,
Maruyama Y.
Department of Neuropsychopharmacology (Tsumura), Gunma University School of Medicine, Japan.

We investigated to find which types of neuronal disturbance in the hypothalamus are responsible for ventromedial hypothalamic nucleus (VMH) lesion-induced development of obesity. We found that in VMH-lesioned obese rats, the contents of norepinephrine (NE) and dopamine in the hypothalamus were selectively decreased, but that the serotonin and acetylcholine levels were unchanged from those in sham controls. Also, the content of NE in the lateral portion of the hypothalamus was decreased. Our results show that disturbance of the hypothalamic noradrenergic and dopaminergic neurons, but not of the serotonergic or cholinergic neurons, contributes to the development of VMH lesion-induced obesity.
PMID: 7882057 [PubMed - indexed for MEDLINE]

1: J Tradit Chin Med. 2001 Sep;21(3):220-4. Links

Study on action of acupuncture on ventromedial nucleus of hypothalamus in obese rats.

Liu Z,
Sun F,
Su J,
Zhao M ,
Zhu M,
Wang Y ,
Wei Q,
Li J,
Gu Y.

Second Clinical Medical College of Nanjing, University of Traditional Chinese Medicine and Pharmacy, Nanjing 210029.

Effects of acupuncture on the spontaneous discharge of nerve cells and levels of monoamine neurotransmitters in ventromedial nucleus of hypothalamus (VMH) of the obese rats were investigated. Results indicated that the levels of tyrosine (Tyr) and dopamine (DA) were lowered, the levels of 5-hydroxytryptamine (5-HT) and 5-hydoxyindole acetic acid (5-HIAA) increased, and the frequency of the spontaneous discharge of nerve cells in VMH lowered in the obese rat group as compared with the normal group. When acupuncture obtained the effect of weight reduction, the frequency of spontaneous discharges of nerve cells in VMH were markedly increased, and the levels of Tyr, DA and tryptamine (Typ) and 5-HT/5-HIAA ratio elevated, and the 5-HT level lowered. It is suggested that the virtuous regulative action of acupuncture on VMH might be one of the key factors in acupuncture for weight reduction.

PMID: 11789333 [PubMed - indexed for MEDLINE]

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